FL fluid bed granulator

1. Working principle of fluidized bed granulator

FL series fluidized bed granulator is also called fluid bed granulator or one step granulator. It is a batch type top spray powder granulation/agglomeration processor which has been widely used in pharmaceutical, chemical and foodstuff industry. Raw material (free-flowing dry powder or small granules ) is loaded in the granulating bowl of which the bottom is made by perforated plate. Clean hot air flows through the perforated plate to completely fluidize the material. Meanwhile, liquid binder is sprayed onto the fluidized material. Fine powder collides with droples and stick together to form granules or agglomerates with good flowability and instant solubility.

2. Technical advantages of fluidized bed granulator
  1. cGMP Design: 150 grit exterior finish, mirror finish on internal surfaces. The system can meet GMP standard;
  2. HEPA air filter: The air filter consists of primary stage, secondary stage and high efficiency stage air filter and the air cleanness can reach 100,000 grade;
  3. Automatic pneumatic sealing: two pneumatic cylinders lift the granulation bowl for sealing with the top chamber; the inflated square rubber ring will seal the bottom chamber to create a completely sealed granulation chamber;
  4. Two-bag-filter-chamber system: The top bag filtering system has two chambers which work alternately to avoid air pressure onto the filter bag. The product rate can reach 99%.
  5. Accurate air flow control: The exhaust fan is combined with Siemens inverter to accurately control the air flow rate for achieving perfect fluidization.
  6. Good working condition: The whole system is working under negative pressure, so there is no powder leaking at all. Exhaust fan is equipped with silencer as well as isolated installation, the noise is below 75 dB(A).
  7. Safety measures: The whole system adopts following measure to 100 % make sure safety during operation:
    1) Function interlocked: All the function buttons in the control panel are interlocked (only proper operation steps can run the system) to prevent any mistakable operation to the machine.
    2) Explosion proof design: Granulation chamber is equipment with venting. When the pressure inside the chamber is getting higher than the rated one (say 2 bar), the rupture membrane will break to release the pressure.
    3) Pressure monitoring: Pressure sensor is equipped to monitor pressure change inside the granulation chamber. When pressure is getting higher (especially when the bag filter is choked) and positive pressure condition is formed, electrical heater and exhaust fan will stop automatically and pressure release valve will open.

3. Technical parameterss of fluidized bed granulator