antiphlogistine

This product is an antifungal pyrrole and a dechlorinated derivative of miconazole.This product has antibacterial effect on candida, staining fungus, coccidioides, histoplasma and sporothrix, and has antibacterial activity on tinea capillaris.This product has poor effect on aspergillus, schenk's sporothrix, some darkcolor sporaceae, mucor, etc.By interfering with the activity of cytochrome p-450, this product inhibits the biosynthesis of ergosteroid, the main steroid in the fungal cell membrane, damages the fungal cell membrane and changes its permeability, resulting in the leakage of important intracellular materials.This product can inhibit the biosynthesis of triacylglycerol and phospholipids of fungi, inhibit the activity of oxidase and peroxidase, and cause the accumulation of hydrogen peroxide in cells leading to submicrostructure degeneration and cell necrosis.Candida albicans inhibits the transformation from spore to invasive hyphae.